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Camphorsulfonic acid
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Camphorsulfonic acid : ウィキペディア英語版
Camphorsulfonic acid

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Camphorsulfonic acid, sometimes abbreviated CSA or 10-CSA is an organosulfur compound. Like typical sulfonic acids, it is a relatively strong acid that is a colorless solid at room temperature and is soluble in water and a wide variety of organic substances.
This compound is commercially available. It can be prepared by sulfonation of camphor with sulfuric acid and acetic anhydride:
:
In organic synthesis, CSA and its derivatives can be used as resolving agents for chiral amines and other cations.〔André B. Charette "3-Bromocamphor-8-sulfonic Acid" Encyclopedia of Reagents for Organic Synthesis 2001, John Wiley & Sons. 〕 For example, 3-bromocamphor-8-sulfonic acid was used in the synthesis of enantiopure devazepide.
*Trimetaphan camsilate (trimethaphan camsylate) is another good example.
==References==


抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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